The influence of the shape of magnetic nanoparticles on magnetic hyperthermia and cellular internalisation

Published in Journal of Alloys and Compounds

2025/11/14

For years, research on magnetic nanoparticles has focused on optimizing their magnetic properties, surface chemistry, and composition to enhance their potential in cancer therapy. However, one important question has remained largely unexplored: How does the shape of a nanoparticle affect its uptake by cancer cells ?

In interdisciplinary study that bridges materials science and biology, we explore this missing piece by studying magnetic nanoparticles with different geometries and investigating how their shape affects cellular interactions and uptake in brain tumor (glioblastoma) cells.

K. Riahi, N. Sommer, A. Filatova, I. Dirba, E. Adabifiroozjaei, L. Molina-Luna, C. Breuer, M. Biesalski, U. A. Nuber, and O. Gutfleisch,
J. Alloys Compd. 1045 (2025) 184692.
DOI: 10.1016/j.jallcom.2025.184692